ICC/IF
Immunofluorescence analysis of C2C12 cells using CIR1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-CIR1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CIRSR |
|---|---|
| Gene Synonyms | CIR CIR1 THE1B/CIR1 |
| Gene Full Name | corepressor of RBPJ and splicing regulator |
| Gene Summary | Enables histone deacetylase binding activity; protein kinase binding activity; and transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in centrosome and nuclear speck. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025] |
| Alternative Names | CBF1 (RBPJ) interacting corepressor 1 CBF1-interacting corepressor corepressor interacting with RBPJ 1 corepressor interacting with RBPJ CIR1 recepin THE1B/CIR1 |
| Molecular Weight(MW) | 52kDa(observed：70kDa) |
| Cellular Localization | Nucleus speckle;Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
| SwissProt ID | Q86X95 |
|---|
ICC/IF
Immunofluorescence analysis of C2C12 cells using CIR1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
