ICC/IF
Immunofluorescence analysis of Hela cells using MB21D1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-MB21D1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CGAS |
|---|---|
| Gene Synonyms | C6orf150 D4 E330016A19Rik h-cGAS MB21D1 |
| Gene Full Name | cyclic GMP-AMP synthase |
| Gene Summary | Enables several functions, including 2',3'-cyclic GMP-AMP synthase activity; molecular condensate scaffold activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including intracellular signal transduction; paracrine signaling; and regulation of defense response. Located in nuclear body; plasma membrane; and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025] |
| Alternative Names | 2'3'-cGAMP synthase C6orf150 C6orf150 cGAS is a cytosolic DNA sensor that induces interferons by producing the second messenger cGAMP cGAMP synthase DANGER family member 4 E330016A19 cGAS is a cytosolic DNA sensor that induces interferons by producing the second messenger cGAMP h-cGAS Mab-21 domain containing 1 mab-21 domain-containing protein 1 MB21D1 protein MB21D1 |
| Molecular Weight(MW) | 58kDa |
| Source | Rabbit |
| Cellular Localization | Nucleus;Chromosome;Cell membrane;Cytoplasm, cytosol |
| SwissProt ID | Q8N884 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using MB21D1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
