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Mouse Monoclonal antibody to cGAS

Catalog Number:OM647006
OM647006
Discount Price
OM647006-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to cGAS
Antibody Type Primary Antibodies
Key Feature
Clonality Monoclonal
Isotype IgG2a,k
Host Species Mouse
Tested Applications IHCWB
WB:1:100-1:1000
IHC:1:50-1:500
Species Reactivity Human
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CGAS
Gene Synonyms D4
MB21D1
h-cGAS
C6orf150
Gene Full Name cyclic GMP-AMP synthase
Gene Summary Enables several functions, including 2',3'-cyclic GMP-AMP synthase activity; molecular condensate scaffold activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including intracellular signal transduction; paracrine signaling; and regulation of defense response. Located in nuclear body; plasma membrane; and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Molecular Weight(MW) 60 kDa
Cellular Localization Cell membrane,Chromosome,Cytoplasm,Membrane,Nucleus.
Application

WB

cGAS Antibody : Mouse Monoclonal antibody to cGAS AF647. Direct fluorescence Western blot analysis of cGAS expression in T24 whole-cell lysate.

IHC

cGAS antibody : Mouse Monoclonal antibody. Formalin fixation and immunoperoxidase staining of paraffin-embedded human bone marrow tissue showed cytoplasmic staining of hematopoietic cells.
Application Notes WB:1:100-1:1000
IHC:1:50-1:500
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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