Enables several functions, including 2',3'-cyclic GMP-AMP synthase activity; molecular condensate scaffold activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including intracellular signal transduction; paracrine signaling; and regulation of defense response. Located in nuclear body; plasma membrane; and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Alternative Names
2'3'-cGAMP synthase C6orf150 C6orf150 cGAS is a cytosolic DNA sensor that induces interferons by producing the second messenger cGAMP cGAMP synthase DANGER family member 4 E330016A19 cGAS is a cytosolic DNA sensor that induces interferons by producing the second messenger cGAMP h-cGAS Mab-21 domain containing 1 mab-21 domain-containing protein 1 MB21D1 protein MB21D1