ICC/IF
Immunofluorescence analysis of U251 cells using YWHAE antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-YWHAE antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | YWHAE |
|---|---|
| Gene Synonyms | 14-3-3E HEL2 KCIP-1 MDCR MDS |
| Gene Full Name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
| Gene Summary | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008] |
| Alternative Names | 14-3-3 epsilon 14-3-3E epididymis luminal protein 2 mitochondrial import stimulation factor (MSF) L subunit mitochondrial import stimulation factor L subunit MSF L protein kinase C inhibitor protein-1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon polypeptide tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activatioprotein epsilon polypeptide tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activatioprotein epsilon polypeptide tyrosine 3/tryptophan 5 -monooxygenase activation protein epsilon polypeptide |
| Molecular Weight(MW) | 29kDa |
| Source | Rabbit |
| Cellular Localization | Nucleus;Cytoplasm;Melanosome |
| SwissProt ID | P62258 |
|---|
ICC/IF
Immunofluorescence analysis of U251 cells using YWHAE antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
