ICC/IF
Immunofluorescence analysis of U251 cells using ROR1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-ROR1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ROR1 |
|---|---|
| Gene Synonyms | 2810404D04Rik dJ537F10.1 NTRKR1 |
| Gene Full Name | ROR family WNT receptor 1 |
| Gene Summary | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012] |
| Alternative Names | MGC99659 neurotrophic tyrosine kinase receptor-related 1 receptor tyrosine kinase like orphan receptor 1 T-ROR1 tyrosine-protein kinase transmembrane receptor ROR1 |
| Molecular Weight(MW) | 104kDa |
| Source | Rabbit |
| Cellular Localization | Membrane;Cell projection, axon |
| SwissProt ID | Q01973 |
|---|
ICC/IF
Immunofluorescence analysis of U251 cells using ROR1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
