| Product Name | Anti-TRAF3 antibody-RBITC |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | RBITC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TRAF3 |
|---|---|
| Gene Synonyms | amn CAP-1 CD40bp CRAF1 IIAE5 IMD132A IMD132B LAP1 RNF118 T-BAM TRAFAMN |
| Gene Full Name | TNF receptor associated factor 3 |
| Gene Summary | The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. The protein also plays a role in the regulation of antiviral response. Mutations in this are associated with Encephalopathy, acute, infection-induced, herpes-specific 5. [provided by RefSeq, Jul 2020] |
| Alternative Names | CD40 associated protein 1 CD40 binding protein CD40 receptor associated factor 1 CD40 receptor-associated factor 1 CD40-binding protein LMP1-associated protein 1 RING-type E3 ubiquitin transferase TRAF3 |
| Molecular Weight(MW) | 64kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm;Endosome;Mitochondrion |
| SwissProt ID | Q13114 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
