| Gene Symbol |
CDK11B
|
| Gene Synonyms |
Cdc11b CDC2L1 CDC2L2 CDC2L3 CDK11 CDK11-p110 CDK11-p46 CDK11-p58 CLK-1 p58 p58CDC2L1 p58CLK-1 p58GTA PITSLRE PITSLREA PK58 |
| Gene Full Name |
cyclin dependent kinase 11B |
| Gene Summary |
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| Alternative Names |
CDC-related protein kinase p58 cell division cycle 2 homolog-like 1 cell division cycle 2 homolog-like 2 cell division cycle 2-like 1 cell division cycle 2-like 1 (PITSLRE proteins) cell division cycle 2-like 2 cell division cycle 2-like 2 (PITSLRE proteins) cell division cycle 2-like protein kinase 1 cell division cycle 2-like protein kinase 2 cell division protein kinase 11 cell division protein kinase 11A cell division protein kinase 11B cyclin-dependent kinase 11 galactosyltransferase-associated protein kinase p58/GTA GR specific protein kinase p58 CLK-1 PITSLRE B PITSLRE proteins PITSLRE serine/threonine-protein kinase CDC2L1 PITSLRE serine/threonine-protein kinase CDC2L2 |
| Molecular Weight(MW) |
92kDa |
| Source |
Rabbit |
| Cellular Localization |
Nucleus;Cytoplasm |