The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
Alternative Names
H-IGF-1 IGF IGF-1 Igf-1 Ea IGF-I Igf-I Eb IGF-IA IGF-IB IGF1 IGF1A IGFIa Insulin like growth factor insulin like growth factor I insulin-like growth factor 1 (somatomedin C) Insulin-like growth factor I insulin-like growth factor I precursor insulin-like growth factor IB insulin-like growth factor IB prepropeptide insulin-like growth factor precursor M-IGF-1 mechano growth factor OTTHUMP00000195084 pre-pro-insulin-like growth factor I R-IGF-1 somatomedin Somatomedin C somatomedin-C