| Gene Symbol |
ST3GAL3
|
| Gene Synonyms |
DEE15 EIEE15 MRT12 Siat3 SIAT6 ST3Gal III ST3GALII ST3GalIII ST3N |
| Gene Full Name |
ST3 beta-galactoside alpha-2,3-sialyltransferase 3 |
| Gene Summary |
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with a form of autosomal recessive nonsymdromic cognitive disability as well as infantile epileptic encephalopathy. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2017] |
| Alternative Names |
alpha 2 3-sialyltransferase III alpha 2 3-ST 3 alpha-2 3-sialyltransferase II beta-galactoside alpha-2 3-sialyltransferase 3 gal beta-1 3(4) GlcNAc alpha-2 3 sialyltransferase Gal beta-1 3(4)GlcNAc alpha-2 3 sialyltransferase N-acetyllacosaminide alpha 2 3-sialyltransferase N-acetyllactosaminide alpha-2 3-sialyltransferase sialyltransferase (N-acetyllacosaminide alpha 23-sialyltransferase) sialyltransferase 3 sialyltransferase 6 (N-acetyllacosaminide alpha 2 3-sialyltransferase) sialyltransferase 6 (N-acetyllactosaminide alpha 2 3-sialyltransferase) sialyltransferase 6(N-acetyllacosaminide alpha 23-sialyltransferase) |
| Molecular Weight(MW) |
42kDa |
| Source |
Rabbit |
| Cellular Localization |
Golgi apparatus, Golgi stack membrane;Secreted |