ICC/IF
Immunofluorescence analysis of Hela cells using YAP1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Product Name | Anti-YAP1 antibody-AF488 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AF488 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Antigen peptide affinity chromatography |
| Gene Symbol | YAP1 |
|---|---|
| Gene Synonyms | cb194 COB1 sb:cb194 si:ch211-181p1.5 si:dkey-3b8.3 wu:fc18c04 YAP YAP-1 YAP2 YAP65 YKI Yorkie zgc:158380 zYAP |
| Gene Full Name | Yes1 associated transcriptional regulator |
| Gene Summary | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] |
| Alternative Names | 65 kDa Yes-associated protein protein yorkie homolog transcription cofactor transcription cofactor YAP transcriptional co-activator yap Yes associated protein 1 Yes-associated protein 1 Yes-associated protein 1 65kDa yes-associated protein 2 yes-associated protein YAP65 homolog yes-associated protein 65 kDa yorkie homolog |
| Molecular Weight(MW) | 54kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm;Nucleus;Cell junction, tight junction;Cell membrane |
| SwissProt ID | P46937 |
|---|
ICC/IF
Immunofluorescence analysis of Hela cells using YAP1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Omnimabs® 594-Phalloidin.| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
