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Anti-Phospho-YAP (Ser127) antibody

Catalog Number:OM682071
OM682071
Discount Price
OM682071-100ul
100ul
Product Profile
Product Name Anti-Phospho-YAP (Ser127) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser127
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol YAP1
Gene Synonyms YAP
YKI
COB1
YAP2
YAP-1
YAP65
Gene Full Name Yes1 associated transcriptional regulator
Gene Summary This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Alternative Names 65 kDa Yes associated protein
65 kDa Yes-associated protein
COB1
YAp 1
YAP 65
YAP
YAP1
YAP1_HUMAN
YAP2
YAP65
yes -associated protein delta
Yes associated protein 1 65kDa
Yes associated protein 1
Yes associated protein 2
yes associated protein beta
YKI
Yorkie homolog
Molecular Weight(MW) 54 kDa
Cellular Localization Cell junction, Cell membrane, Cytoplasm, Membrane, Nucleus, Tight junction.
Database Links
SwissProt ID P46937
Application

ELISA

Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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