This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Alternative Names
65 kDa Yes-associated protein protein yorkie homolog transcription cofactor transcription cofactor YAP transcriptional co-activator yap Yes associated protein 1 Yes-associated protein 1 Yes-associated protein 1 65kDa yes-associated protein 2 yes-associated protein YAP65 homolog yes-associated protein 65 kDa yorkie homolog