| Gene Symbol |
YAP1
|
| Gene Synonyms |
cb194 COB1 sb:cb194 si:ch211-181p1.5 si:dkey-3b8.3 wu:fc18c04 YAP YAP-1 YAP2 YAP65 YKI Yorkie zgc:158380 zYAP |
| Gene Full Name |
Yes1 associated transcriptional regulator |
| Gene Summary |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] |
| Alternative Names |
65 kDa Yes-associated protein protein yorkie homolog transcription cofactor transcription cofactor YAP transcriptional co-activator yap Yes associated protein 1 Yes-associated protein 1 Yes-associated protein 1 65kDa yes-associated protein 2 yes-associated protein YAP65 homolog yes-associated protein 65 kDa yorkie homolog |
| Molecular Weight(MW) |
54kDa |
| Source |
Rabbit |
| Cellular Localization |
Cytoplasm;Nucleus;Cell junction, tight junction;Cell membrane |