This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.[provided by RefSeq, Sep 2010]
Alternative Names
adenomatosis polyposis coli down-regulated 1 protein adenomatosis polyposis coli down-regulated 1 protein homolog APCDD1 (HGNC:15718) APCDD1 homologue ethanol induced gene product EIG180 hypoptrichosis simplex primglo1 protein primglo1