Enables GTPase activator activity. Involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and negative regulation of kinase activity. Part of GATOR1 complex. Is active in lysosomal membrane. Implicated in familial focal epilepsy with variable foci 2. [provided by Alliance of Genome Resources, Jul 2025]
Alternative Names
2810446G01Rik G21 protein GATOR complex protein NPRL2 gene 21 protein homologous to yeast nitrogen permease (candidate tumor suppressor) mutant NPRL2 nitrogen permase homolog nitrogen permease regulator 2-like protein nitrogen permease regulator-like 2 NPR 2L NPR L2 NPR like 2 NPR2 like NPR2-like protein NPRL 2 similar to yeast NPR2 nitrogen permease regulator tumor suppressor candidate 4 TUSC 4 TUSC 4 protein TUSC4 TUSC4 protein