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Anti-PDGFR beta antibody

Catalog Number:OM662777
OM662777
Discount Price
OM662777-100ul
100ul
OM662777-50ul
50ul
OM662777-20ul
20ul
Product Profile
Product Name Anti-PDGFR beta antibody
Antibody Type Primary Antibodies
Product description

 

 
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISAICC/IF
ELISA:1:1000-10000
ICC/IF:1:100-1:500
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Antigen peptide affinity chromatography
Target Information
Gene Symbol PDGFRB
Gene Synonyms CD140B
IBGC4
IMF1
JTK12
KOGS
OPDKD
PDGFR
PDGFR-1
PDGFR1
PENTT
Gene Full Name platelet derived growth factor receptor beta
Gene Summary The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]
Alternative Names Activated tyrosine kinase PDGFRB
beta platelet-derived growth factor receptor
beta-type platelet-derived growth factor receptor
CD140 antigen-like family member B
CD140b antigen
PDGF beta chain
PDGF Receptor beta
PDGF-R-beta
PDGFR-beta
platelet derived growth factor receptor
beta polypeptide
platelet-derived growth factor receptor 1
Platelet-derived growth factor receptor
beta
platelet-derived growth factor receptor
beta polypeptide
V1-Pdgfrb
Molecular Weight(MW) 122kDa
Source Rabbit
Cellular Localization Cell membrane;Cytoplasmic vesicle;Lysosome lumen
Database Links
SwissProt ID P05622
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-10000
ICC/IF:1:100-1:500
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300,40% Glycerol.
validation
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