SET domain containing 1A, histone lysine methyltransferase
Gene Summary
The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily. [provided by RefSeq, Dec 2016]
Alternative Names
hSET1A lysine N-methyltransferase 2F non-selective cation channel 1 SET domain-containing protein 1A set1/Ash2 histone methyltransferase complex subunit SET1