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Anti-PLC-gamma-1 antibody

Catalog Number:OM663160
OM663160
Discount Price
OM663160-100ul
100ul
OM663160-50ul
50ul
OM663160-20ul
20ul
Product Profile
Product Name Anti-PLC-gamma-1 antibody
Antibody Type Primary Antibodies
Product description

 

 
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-1:10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol PLCG1
Gene Synonyms Cded
IDAA
NCKAP3
Plc-1
Plc-gamma1
PLC-II
PLC1
PLC148
Plcg-1
PLCgamma1
PPLCA
Gene Full Name phospholipase C gamma 1
Gene Summary The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alternative Names 1-phosphatidyl-D-myo-inositol-4
5-bisphosphate
cell differentiation and embryonic development
EC 3.1.4.11
inositoltrisphosphohydrolase
monophosphatidylinositol phosphodiesterase
OTTHUMP00000178982
phosphatidylinositol phospholipase C
phosphoinositidase C
phosphoinositide phospholipase C
phosphoinositide phospholipase C-gamma-1
phospholipase C
phospholipase C
gamma 1 (formerly subtype 148)
phospholipase C-1
phospholipase C-148
phospholipase C-gamma
phospholipase C-II
Phospholipase C2
PLC gamma1
PLC-148
PLC-gamma-1
PLC-II
PLC2I
similar to PLC gamma 1
triphosphoinositide phosphodiesterase
Molecular Weight(MW) 148kDa
Source Rabbit
Cellular Localization Cell projection, lamellipodium;Cell projection, ruffle
Database Links
SwissProt ID P19174
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-1:10000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300,40% Glycerol.
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