The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Alternative Names
C-type lectin domain family 4 member J CD23 antigen FC epsilon RII Fc fragment of IgE receptor II Fc fragment of IgE low affinity II receptor for (CD23) Fc-epsilon receptor old gene name 'FCE1A' fc-epsilon-RII FcepsilonRII FceRII IgE receptor immunoglobulin E-binding factor immunoglobulin epsilon-chain low affinity IgE receptor (Fc-epsilon-RII) low-affinity IgE receptor lymphocyte IgE receptor