This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]
Alternative Names
1-Dec basic helix-loop-helix domain containing class B 2 basic helix-loop-helix domain containing class B2 BHLHB2 class B basic helix-loop-helix protein 2 contains basic helix-loop-helix structure cytokine response gene 8 differentially expressed in chondrocytes 1 differentially expressed in chondrocytes protein 1 differentiated embryo chondrocyte expressed gene 1 E47 interaction protein 1 eip1 (E47 interaction protein 1) enhancer-of-split and hairy-related protein 2 FLJ99214 stimulated by retinoic acid 14 stimulated by retinoic acid gene 13 protein