ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Product Name | Anti-MEK3+MEK6 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description |
|
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA:1:1000-10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MAP2K3 |
|---|---|
| Gene Synonyms | MAPKK 3 MAPKK3 MEK3 MKK3 MKK3b PRKMK3 SAPKK-2 SAPKK2 |
| Gene Full Name | mitogen-activated protein kinase kinase 3 |
| Gene Summary | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | dual specificity mitogen-activated protein kinase kinase 3-like EC 2.7.12.2 MAP kinase kinase 3 MAP2K3 MAPK/ERK kinase 3 MAPKK 3 MEK 3 SAPK kinase 2 stress-activated protein kinase kinase 2 |
| Molecular Weight(MW) | 39kDa |
| Source | Rabbit |
| Cellular Localization | cytoplasm;cytosol;membrane;nucleoplasm;Complete GO annotation on QuickGO |
| SwissProt ID | P46734 |
|---|
ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Application Notes | ELISA:1:1000-10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
