ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Product Name | Anti-CD42b antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description |
|
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA:1:1000-10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | GP1BA |
|---|---|
| Gene Synonyms | BDPLT1 BDPLT3 BSS CD42B CD42b-alpha DBPLT3 GP-Ib alpha GP1B GPIbA GPIbalpha HPA-2 VWDP |
| Gene Full Name | glycoprotein Ib platelet subunit alpha |
| Gene Summary | Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. [provided by RefSeq, Oct 2013] |
| Alternative Names | antigen CD42b-alpha CD42a glycoprotein 1b alpha polypeptide glycoprotein Ib (platelet) alpha polypeptide glycoprotein Ib platelet alpha subunit glycoprotein Ibalpha GP-Ib alpha GP-IX GPIB GPIb alpha GPIX human platelet antigen 2 MGC34595 mutant platelet membrane glycoprotein Ib-alpha platelet glycoprotein Ib alpha chain precursor Platelet GPIX platelet membrane glycoprotein 1b-alpha subunit platelet membrane glycoprotein Ib-alpha |
| Molecular Weight(MW) | 71kDa |
| Source | Rabbit |
| Cellular Localization | Membrane |
| SwissProt ID | P07359 |
|---|
ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Application Notes | ELISA:1:1000-10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300,40% Glycerol. |
