Enables several functions, including importin-alpha family protein binding activity; protein kinase binding activity; and protein serine/threonine kinase activator activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; nucleoplasm; and spindle. Is active in spindle. [provided by Alliance of Genome Resources, Jun 2026]
Alternative Names
C20orf2 differentially expressed in cancerous and non-cancerous lung cells 2 differentially expressed in cancerous and noncancerous lung cells 2 differentially expressed in lung cells GD: HCA519 HCA90 hepatocellular carcinoma-associated antigen 519 hepatocellular carcinoma-associated antigen 90 LCA519 protein preferentially expressed in colorectal cancer protein fls353 restricted expression proliferation associated protein 100 TPX 2 TPX2 microtubule-associated protein homolog TPX2 microtubule-associated homolog
Molecular Weight(MW)
85kDa
Source
Rabbit
Cellular Localization
Nucleus;Cytoplasm, cytoskeleton, spindle;Cytoplasm, cytoskeleton, spindle pole