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Anti-CD162/PSGL-1 antibody

Catalog Number:OM663398
OM663398
Discount Price
OM663398-100ul
100ul
OM663398-50ul
50ul
OM663398-20ul
20ul
Product Profile
Product Name Anti-CD162/PSGL-1 antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-1:10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol SELPLG
Gene Synonyms CD162
CLA
PSGL-1
PSGL1
Gene Full Name selectin P ligand
Gene Summary This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
Alternative Names Cutaneous lymphocyte associated antigen
cutaneous lymphocyte-associated associated antigen
SELPG
Molecular Weight(MW) 43kDa
Source Rabbit
Cellular Localization Membrane
Database Links
SwissProt ID Q14242
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-1:10000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300.
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