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Anti-BIM antibody

Catalog Number:OM663478
OM663478
Discount Price
OM663478-100ul
100ul
OM663478-50ul
50ul
OM663478-20ul
20ul
Product Profile
Product Name Anti-BIM antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-1:10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol BCL2L11
Gene Synonyms 1500006F24Rik
BAM
bcl2-L-11
BIM
BimL
BOD
Gene Full Name BCL2 like 11
Gene Summary The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013]
Alternative Names alternatively spliced
bcl-2 interacting mediator of cell death
bcl-2 interacting protein Bim
Bcl-2 like 11
Bcl-2 related apoptotic gene product BimL
bcl-2-related ovarian death agonist
bcl-2-related ovarian death protein
Bcl2 interacting mediator of cell death
bcl2-interacting mediator of cell death
BCL2-like 11 (apoptosis facilitator)
BCL2L11
BH3 domain containing protein
Bim EL
Bim-A
Bim-alpha3
pro-apoptotic
Bim-alpha4
contains new exon
pro-apoptotic
Bim-alpha5
contains new exon
pro-apoptotic
BIM-alpha6
BIM-beta6
BIM-beta7
OTTHUMP00000197013
OTTHUMP00000204247
proapoptosis factor
Bim alpha 3
BLC2L11
proapoptosis factor
BimS
BCL2L11
proapoptotic BH-3
Bim splice variant
Molecular Weight(MW) 22kDa
Source Rabbit
Cellular Localization Endomembrane system;Mitochondrion
Database Links
SwissProt ID O43521
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-1:10000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300.
validation
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