This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
Alternative Names
aurora kinase B-Sv1 aurora kinase B-Sv2 aurora- and Ipl1-like midbody-associated protein 1 aurora- and Ipl1-like midbody-associated protein 1 homolog aurora-1 aurora-B aurora-related kinase 2 aurora/IPL1-related kinase 2 protein phosphatase 1 regulatory subunit 48 serine/threonine kinase 12 serine/threonine-protein kinase 12 serine/threonine-protein kinase 5 serine/threonine-protein kinase aurora-B