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Anti-CRK antibody

Catalog Number:OM663536
OM663536
Discount Price
OM663536-100ul
100ul
OM663536-50ul
50ul
OM663536-20ul
20ul
Product Profile
Product Name Anti-CRK antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-1:10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CRK
Gene Synonyms c-Crk
Crk-I
Crk-II
Crk-III
CRK1
Crk3
CRKII
CrkIII
Crko
CSBP
CSBP1
CSBP2
CSPB1
EXIP
Hog
Mxi2
p38
p38-alpha
p38a
p38ALPHA
p38Hog
p38MAPK
PRKM14
PRKM15
RK
SAPK2A
Gene Full Name CRK proto-oncogene, adaptor protein
Gene Summary This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
Alternative Names avian sarcoma virus CT10 (v-crk) oncogene homolog
CRK-II
Crk3
CSAID-binding protein
Csaids binding protein
CT-10 related kinase 3
cytokine suppressive anti-inflammatory drug binding protein
cytokine-supressive anti-inflammatory drug binding protein
encoded by transcript variant 4
p38 MAP kinase
encoded by transcript variant 5
p38 MAP kinase
MAP kinase 14
MAP kinase 2
MAP kinase Mxi2
MAP kinase p38 alpha
MAPK 14
MAPK14
MAX-interacting protein 2
mitogen-activated protein kinase 14A
mitogen-activated protein kinase p38 alpha
negative regulator of Crk tyrosine-phosphorylation
p38
p38 kinase
p38 MAP kinase
p38 MAP kinase alpha
p38 MAPK
p38 mitogen activated protein kinase
p38alpha Exip
proto-oncogene C-crk
reactive kinase
SAPK2a
CSAIDS binding protein 1
stress-activated protein kinase 2A
v-crk avian sarcoma virus CT10 oncogene homolog
v-crk sarcoma virus CT10 oncogene homolog
v-crk sarcoma virus CT10 oncogene homolog (avian) isoform CRK_1
v-crk sarcoma virus CT10 oncogene homolog (avian) isoform CRK_2
v-crk sarcoma virus CT10 oncogene-like protein
Molecular Weight(MW) 33kDa
Source Rabbit
Cellular Localization Cytoplasm;Cell membrane
Database Links
SwissProt ID P46108
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-1:10000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300.
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