ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Product Name | Anti-FGF Receptor 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA:1:1000-1:10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | FGFR1 |
|---|---|
| Gene Synonyms | bFGF-R bFGF-R-1 BFGFR c-fgr CD331 CEK Eask ECCL FGFBR FGFR-1 FGFR-I FLG FLT-2 FLT2 Fr1 HBGFR HH2 HRTFDS Hspy KAL2 MFR N-SAM OGD |
| Gene Full Name | fibroblast growth factor receptor 1 |
| Gene Summary | The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
| Alternative Names | 2.7.10.1 basic fibroblast growth factor receptor 1 bFGF-R-1 CD331 antigen cek1 protein cek1 protein precursor FGF Receptor FGF receptor precursor FGF receptor-1 FGF receptor-1 precursor FGFR fgfr 1 FGFR-1 FGFR1-IIIb receptor tyrosine kinase FGFR1/PLAG1 fusion fibroblast growth factor receptor (FGFr) transmembrane form fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2 Pfeiffer syndrome) fibroblast growth factor receptor 1-IIIc fibroblast growth factor receptor FGFR-1 secreted form fibroblast growth factor-receptor precursor FMS-like tyrosine kinase 2 fms-related tyrosine kinase 2 heparin-binding growth factor receptor hydroxyaryl-protein kinase orf 5' of fibroblast growth factor receptor 1 FGFR-1 proto-oncogene c-Fgr soluble form FGF-R1 tyrosine kinase receptor CEK1 |
| Molecular Weight(MW) | 91kDa |
| Source | Rabbit |
| Cellular Localization | Cell membrane ;Nucleus;Cytoplasm, cytosol;Cytoplasmic vesicle |
| SwissProt ID | P11362 |
|---|
ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Application Notes | ELISA:1:1000-1:10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
