| Product Name | Anti-ADA antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ADA |
|---|---|
| Gene Synonyms | ADA1 |
| Gene Full Name | adenosine deaminase |
| Gene Summary | This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine in the purine catabolic pathway. Various mutations have been described for this gene and have been linked to human diseases related to impaired immune function such as severe combined immunodeficiency disease (SCID) which is the result of a deficiency in the ADA enzyme. In ADA-deficient individuals there is a marked depletion of T, B, and NK lymphocytes, and consequently, a lack of both humoral and cellular immunity. Conversely, elevated levels of this enzyme are associated with congenital hemolytic anemia. [provided by RefSeq, Sep 2019] |
| Alternative Names | Ada adenosine aminohydrolase adenosine deaminase (EC 3.5.4.4) RP11-61L14.5 |
| Molecular Weight(MW) | 40kDa |
| Source | Rabbit |
| Cellular Localization | Cell membrane;Cell junction;Cytoplasmic vesicle lumen;Cytoplasm;Lysosome |
| SwissProt ID | P00813 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
