| Product Name | Anti-UBE1L antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | UBA7 |
|---|---|
| Gene Synonyms | 1300004C08Rik D8 UBA1B UBE1L UBE2 UBE7 |
| Gene Full Name | ubiquitin like modifier activating enzyme 7 |
| Gene Summary | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008] |
| Alternative Names | MGC12713 similar to ubiquitin activating enzymes UBA1 ubiquitin-activating enzyme E1 homolog B UBA7 ubiquitin-activating enzyme E1 ubiquitin-activating enzyme 7 ubiquitin-activating enzyme E1 homolog ubiquitin-activating enzyme E1-related protein ubiquitin-activating enzyme-2 |
| Molecular Weight(MW) | 111kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm;Nucleus |
| SwissProt ID | P41226 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
