| Gene Symbol |
MAPK3
|
| Gene Synonyms |
9030612K14Rik ERK ERK-1 ERK-2 ERK1 ERK2 ERT1 ERT2 Esrk1 HS44KDAP HUMKER1A MAPK1 MAPK2 MNK1 Mtap2k NS13 p38 p40 p41 p41mapk p42-MAPK P42MAPK p44 p44-ERK1 p44-MAPK P44ERK1 P44MAPK PRKM1 PRKM2 PRKM3 |
| Gene Full Name |
mitogen-activated protein kinase 3 |
| Gene Summary |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008] |
| Alternative Names |
ERK-2 erk1 erk2 Erk1 cancer susceptibility protein ERK1 MAP kinase mitogen-activated protein kinase ERK1b ERK1c Erk2 cancer susceptibility protein ERT1 extracellular signal-regulated kinase 1 extracellular signal-regulated kinase 2 extracellular signal-related kinase 1 extracellular-signal-regulated kinase 2 insulin-stimulated MAP2 kinase MAP kinase 1 MAP kinase 2 MAP kinase 3 MAPK 1 MAPK 2 MAPK 3 microtubule-associated protein 2 kinase mitogen-activated 3 mitogen-activated protein kinase 1 mitogen-activated protein kinase 2 p42 p42 MAP Kinase p42-MAPK p44 MAP kinase p44/42 MAPK pp42/MAP kinase protein serine/threonine kinase ERK1b protein tyrosine kinase ERK2 |
| Molecular Weight(MW) |
43kDa |
| Source |
Rabbit |
| Cellular Localization |
Cytoplasm;NucleusMembrane, caveola;Cell junction, focal adhesion |