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CCR7 Rabbit mAb

Catalog Number:OM670749
OM670749
Discount Price
OM670749-100ul
100ul
OM670749-50ul
50ul
Product Profile
Product Name CCR7 Rabbit mAb
Antibody Type Primary Antibodies
Immunogen The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications ELISAIFIHCIPWB
IHC1:2000-1:10000 WB1:2000-1:10000 IF1:200-1:1000 ELISA1:5000-1:20000 IP1:50-1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CCR7
Gene Synonyms BLR2
EBI1
CCR-7
CD197
CDw197
CMKBR7
CC-CKR-7
Gene Full Name C-C motif chemokine receptor 7
Gene Summary The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Alternative Names CCR7
CMKBR7
EBI1
EVI1
C-C chemokine receptor type 7
C-C CKR-7
CC-CKR-7
CCR-7
BLR2
CDw197
Epstein-Barr virus-induced G-protein coupled receptor 1
EBI1
EBV-induced G-protein coupled receptor 1
MIP-3 beta receptor
CD antigen CD19
Molecular Weight(MW) 43 kDa
Cellular Localization Cell membrane,Membrane
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-CCR7 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody. Lane 1: K562 Lane 2: Hela Lane 3: 3T3-L1 Lane 4: Rat brain Predicted band size: 43kDa Observed band size: 43kDa

IHC

Human spleen was stained with anti-CCR7 Rabbit antibody
Application Notes IHC1:2000-1:10000 WB1:2000-1:10000 IF1:200-1:1000 ELISA1:5000-1:20000 IP1:50-1:200
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year (Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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