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Anti-IFN beta Antibody

Catalog Number:OM670763
OM670763
Discount Price
OM670763-100ul
100ul
OM670763-50ul
50ul
Product Profile
Product Name Anti-IFN beta Antibody
Antibody Type Primary Antibodies
Immunogen KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IFN beta. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications WB
WB:1:500-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol IFNB1
Gene Synonyms IFB
IFF
IFNB
IFN-beta
Gene Full Name interferon beta 1
Gene Summary This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]
Alternative Names IFB
IFNB
Interferon beta
IFN-beta
Fibroblast interferon
Molecular Weight(MW) 22 kD; Observed band size: 22 kD)
Cellular Localization Secreted
Application

WB

estern blot analysis of IFN beta expression in HepG2 (A), mouse liver (B), rat liver (C) whole cell lysates. (Predicted band size: 22 kD; Observed band size: 22 kD)
Application Notes WB:1:500-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Storage Buffer Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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