estern blot analysis of IFN beta expression in HepG2 (A), mouse liver (B), rat liver (C) whole cell lysates. (Predicted band size: 22 kD; Observed band size: 22 kD)
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IFN beta. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:1000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
IFNB1
Gene Synonyms
IFB IFF IFNB IFN-beta
Gene Full Name
interferon beta 1
Gene Summary
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]
estern blot analysis of IFN beta expression in HepG2 (A), mouse liver (B), rat liver (C) whole cell lysates. (Predicted band size: 22 kD; Observed band size: 22 kD)
Application Notes
WB:1:500-1:1000
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.