IHC
Immunohistochemistry of paraffin-embedded human glioma using Rabbit anti-SMOX Polyclonal antibody at dilution of 1:100.ICC/IF
Immunofluorescent analysis of A549 cells using Rabbit anti-SMOX Polyclonal antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Product Name | Rabbit anti-SMOX Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Spermine oxidase protein (268-353AA). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC |
| IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | SMOX |
|---|---|
| Gene Synonyms | PAO SMO PAO1 PAOH PAO-1 PAOH1 C20orf16 |
| Gene Full Name | spermine oxidase |
| Gene Summary | Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012] |
| Alternative Names | SMOX antibody C20orf16 antibody SMO antibody UNQ3039/PRO9854 antibody Spermine oxidase antibody EC 1.5.3.16 antibody Polyamine oxidase 1 antibody PAO-1 antibody PAOh1 antibody |
| Cellular Localization | Cytoplasm,Nucleus. |
| SwissProt ID | Q9NWM0 |
|---|
IHC
Immunohistochemistry of paraffin-embedded human glioma using Rabbit anti-SMOX Polyclonal antibody at dilution of 1:100.
ICC/IF
Immunofluorescent analysis of A549 cells using Rabbit anti-SMOX Polyclonal antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Application Notes | IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
|---|---|
| Storage Buffer | Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. |
