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In vivo Grade Recombinant Anti-mouse CTLA-4, Mouse IgG2a-LALAPG Kappa (Clone: 9D9)

Catalog Number:OM680056
OM680056
Discount Price
OM680056-1mg
1mg
OM680056-5mg
5mg
OM680056-25mg
25mg
Product Profile
Product Name In vivo Grade Recombinant Anti-mouse CTLA-4, Mouse IgG2a-LALAPG Kappa (Clone: 9D9)
Product description

Recombinant Mouse IgG2a-LALAPG Monoclonal Antibody. 
Clone: 9D9.
Isotype: Mouse IgG2a kappa.
Source: The anti-mouse CTLA-4 monoclonal antibody (clone: 9D9) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 9D9) specifically binds to the mouse CTLA-4 protein.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CTLA-4 protein. 
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions.

Shipping: The antibody is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

 
Target Information
Function The 9D9 antibody blocks the mouse cytotoxic T lymphocyte antigen-4 (CTLA-4). Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is an inhibitory molecule that competes with the stimulatory CD28 for binding to B7 on antigen presenting cells. CTLA-4 and CD28 are both presented on the surface of T-cells.
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