| Product Name | In vivo Grade Recombinant Anti-mouse CD19 (Clone: 1D3), Rat IgG2a Kappa |
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| Product description | Recombinant rat IgG2a Monoclonal Antibody. Shipping: The antibody is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Function | The 1D3 antibody binds to the mouse CD19 protein, a transmembrane protein expressed in all B lineage cells including mouse plasma cells. CD19 plays two major roles in mouse B cells: it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane, and works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. CD19 is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies. |
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