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CD38 Rabbit mAb

Catalog Number:OM680440
OM680440
Discount Price
OM680440-100ul
100ul
OM680440-50ul
50ul
OM680440-20ul
20ul
Product Profile
Product Name CD38 Rabbit mAb
Antibody Type Primary Antibodies
Key Feature
Clonality monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications IHCWB
WB:1:1000-1:5000
IHC:1:200-1:1000
Species Reactivity MouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CD38
Gene Synonyms ADPRC1
cADPR1
ADPRC 1
Gene Full Name CD38 molecule
Gene Summary The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Alternative Names CD38
ADP-ribosyl cyclase 1
Cyclic ADP-ribose hydrolase 1
cADPr hydrolase 1
T10
CD antigen CD38
Molecular Weight(MW) 34kDa(Observed MW 45kDa)
Cellular Localization Membrane.
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-CD38 antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Mouse spleen Lane 2: Rat spleen.

IHC

Rat pancreas was stained with anti-CD38 rabbit antibody.

IHC

Mouse pancreas was stained with anti-CD38 rabbit antibody.
Application Notes WB:1:1000-1:5000
IHC:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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