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Anti-DSG1 Antibody

Catalog Number:OM680502
OM680502
Discount Price
OM680502-100ul
100ul
OM680502-50ul
50ul
OM680502-20ul
20ul
Product Profile
Product Name Anti-DSG1 Antibody
Antibody Type Primary Antibodies
Immunogen A synthesized peptide derived from human DSG1.
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
WB:1:500-2000
IHC:1:50-200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol DSG1
Gene Synonyms DG1
DSG
CDHF4
EPKHE
PPKS1
SPPK1
EPKHIA
Gene Full Name desmoglein 1
Gene Summary This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]
Alternative Names Cadherin family member 4
CDHF4
desmoglein 1
Desmosomal glycoprotein 1
DG1
DGI
DSG
DSG1
Pemphigus foliaceus antigen
PPKS1
SPPK1
Molecular Weight(MW) 114kDa(Observed MW 114kDa)
Cellular Localization Nucleus
Application

WB

Western blot analysis of DSG1 expression in human skin lysate.

IHC

IHC analysis of DSG1 using anti-DSG1 antibody. DSG1 was detected in a paraffin-embedded section of human lung cancer tissue. The tissue section was incubated with rabbit anti-DSG1 Antibody at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit with DAB as the chromogen.

IHC

IHC analysis of DSG1 using anti-DSG1 antibody. DSG1 was detected in a paraffin-embedded section of mouse testis tissue. The tissue section was incubated with rabbit anti-DSG1 Antibody at a dilution of 1:200 and developed using HRP Conjugated Rabbit IgG Super Vision Assay Kit with DAB as the chromogen.
Application Notes WB:1:500-2000
IHC:1:50-200
Additional Information
Form Liquid
Storage Instructions 12 months from date of receipt,-20℃ as supplied.
Storage Buffer 500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
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