ELISA
Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide| Product Name | Anti-Phospho-BTK(Tyr551) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Tyr551 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BTK |
|---|---|
| Gene Synonyms | AT ATK BPK XLA IMD1 AGMX1 IGHD3 PSCTK1 |
| Gene Full Name | Bruton tyrosine kinase |
| Gene Summary | The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013] |
| Alternative Names | Agammaglobulinaemia tyrosine kinase AGMX 1 AGMX1 AT ATK B cell progenitor kinase B-cell progenitor kinase BPK Bruton agammaglobulinemia tyrosine kinase Bruton tyrosine kinase Bruton’s Tyrosine Kinase Btk BTK_HUMAN dominant-negative kinase-deficient Brutons tyrosine kinase IMD 1 IMD1 MGC126261 MGC126262 OTTHUMP00000063593 PSCTK 1 PSCTK1 truncated Bruton agammaglobulinemia tyrosine kinase Tyrosine protein kinase BTK Tyrosine-protein kinase BTK tyrosine-protein kinase BTK isoform (lacking exon 14 XLA |
| Molecular Weight(MW) | 76kDa |
| Cellular Localization | Cytoplasm |
| SwissProt ID | Q06187 |
|---|
ELISA
Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
