| Gene Symbol |
CENPA
|
| Gene Synonyms |
CenH3 CENP-A |
| Gene Full Name |
centromere protein A |
| Gene Summary |
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015] |
| Alternative Names |
CENP A CENP-A cenpa CENPA_HUMAN Centromere autoantigen A Centromere protein A 17kDa Centromere protein A Histone H3 like centromeric protein A Histone H3-like centromeric protein A
|
| Molecular Weight(MW) |
16kDa |
| Cellular Localization |
Centromere,Chromosome,Nucleosome core,Nucleus |