| Product Name | Anti-Phospho-NF kappaB p100/p52(Ser870) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser870 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NFKB2 |
|---|---|
| Gene Synonyms | p52 p100 H2TF1 LYT10 CVID10 LYT-10 NF-kB2 p49/p100 |
| Gene Full Name | nuclear factor kappa B subunit 2 |
| Gene Summary | This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
| Alternative Names | CVID10 DNA binding factor KBF2 H2TF1 Lymphocyte translocation chromosome 10 protein LYT 10 NF kB2 NFKB p52/p100 subunit Nuclear factor Kappa B subunit 2 Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 (p49/p100) Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 Oncogene Lyt 10 p100 Transcription factor NFKB2 |
| Molecular Weight(MW) | 97 kDa |
| Cellular Localization | Cytoplasm,Nucleus. |
| SwissProt ID | Q00653 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
