| Product Name | Anti-Phospho-Ret(Tyr1062) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr1062 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RET |
|---|---|
| Gene Synonyms | PTC MTC1 HSCR1 MEN2A MEN2B CDHF12 CDHR16 RET-ELE1 |
| Gene Full Name | ret proto-oncogene |
| Gene Summary | This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. |
| Alternative Names | C ret antibody Cadherin family member 12 antibody Cadherin related family member 16 antibody CDHF 12 antibody CDHF12 antibody CDHR16 antibody ELKS Fusion gene antibody HSCR 1 antibody HSCR1 antibody Hydroxyaryl protein kinase antibody MEN2A antibody MEN2B antibody MTC 1 antibody MTC1 antibody Multiple endocrine neoplasia and medullary thyroid carcinoma 1 antibody Oncogene RET antibody Proto oncogene tyrosine protein kinase receptor ret antibody Proto-oncogene c-Ret antibody Proto-oncogene tyrosine-protein kinase receptor ret antibody PTC antibody RET antibody RET ELE1 antibody Ret Proto oncogene antibody RET transforming sequence antibody RET_HUMAN antibody RET51 antibody RET9 antibody tyrosine-protein kinase receptor ret antibody |
| Molecular Weight(MW) | 124 kDa |
| Cellular Localization | Cell membrane, Endosome membrane. |
| SwissProt ID | P07949 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
