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Anti-Phospho-CD45(Ser1007)[Ser1009] Antibody

Catalog Number:OM681544
OM681544
Discount Price
OM681544-100ul
100ul
Product Profile
Product Name Anti-Phospho-CD45(Ser1007)[Ser1009] Antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser1007
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PTPRC
Gene Synonyms LCA
LY5
B220
CD45
L-CA
T200
CD45R
GP180
IMD105
Gene Full Name protein tyrosine phosphatase receptor type C
Gene Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Alternative Names B220 antibody
CD 45 antibody
CD45 antibody
CD45 antigen antibody
CD45R antibody
GP180 antibody
L-CA antibody
LCA antibody
Leukocyte common antigen antibody
loc antibody
Ly-5 antibody
LY5 antibody
Ly5
homolog of antibody
Lyt-4 antibody
OTTHUMP00000033813 antibody
OTTHUMP00000033816 antibody
OTTHUMP00000033817 antibody
OTTHUMP00000038574 antibody
Protein tyrosine phosphatase receptor type c polypeptide antibody
Protein tyrosine phosphatase
receptor type C antibody
protein tyrosine phosphatase
receptor type
C antibody
Protein tyrosine phosphatase
receptor type
c polypeptide antibody
Ptprc antibody
PTPRC_HUMAN antibody
Receptor-type tyrosine-protein phosphatase C antibody
T200 antibody
T200 glycoprotein antibody
T200 leukocyte common antigen antibody
Molecular Weight(MW) 145 kDa
Cellular Localization Cell membrane, Membrane raft, Synapse.
Database Links
SwissProt ID P08575
Application

ELISA

Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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