| Gene Symbol |
G3BP1
|
| Gene Synonyms |
G3BP HDH-VIII |
| Gene Full Name |
G3BP stress granule assembly factor 1 |
| Gene Summary |
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] |
| Alternative Names |
ATP dependent DNA helicase VIII ATP-dependent DNA helicase VIII G3BP G3BP stress granule assembly factor 1 G3BP-1 G3bp1 G3BP1_HUMAN GAP binding protein GAP SH3 domain binding protein 1 GAP SH3 domain-binding protein 1 GTPase activating protein (SH3 domain) binding protein 1 hDH VIII Human DNA helicase VIII MGC111040 Ras GTPase activating protein binding protein 1 Ras GTPase activating protein SH3 domain binding protein Ras GTPase-activating protein-binding protein 1 RasGAP associated endoribonuclease G3BP
|
| Molecular Weight(MW) |
52kDa |
| Cellular Localization |
Cytoplasm, Nucleus |