| Product Name | Anti-Phospho-Gab2(Tyr643) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr643 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GAB2 |
|---|---|
| Gene Full Name | GRB2 associated binding protein 2 |
| Gene Summary | This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009] |
| Alternative Names | GAB 2 Gab2 GAB2_HUMAN Grb 2 associated binder 2 GRB 2 associated binding protein 2 Grb2 associated binder 2 GRB2 associated binder 2 pp100 GRB2 associated binding protein 2 GRB2-associated binder 2 GRB2-associated-binding protein 2 Growth factor receptor bound protein 2 associated protein 2 Growth factor receptor bound protein 2-associated protein 2 KIAA0571 p97 PH domain containing adaptor molecule p97 pp100 |
| Molecular Weight(MW) | 74 kDa |
| Cellular Localization | Cell membrane,Cytoplasm,Membrane. |
| SwissProt ID | Q9UQC2 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
