| Product Name | Anti-Phospho-CDC25B (Ser353) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser353 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDC25B |
|---|---|
| Gene Synonyms | MPIP2 |
| Gene Full Name | cell division cycle 25B |
| Gene Summary | CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008] |
| Alternative Names | AI604853 Cdc 25B Cdc25b CDC25HU2 Cdc25m2 Cell division cycle 25 homolog B Cell division cycle 25B Cell division cycle 25B isoform 1 Cell division cycle 25B isoform 2 Cell division cycle 25B isoform 3 Cell division cycle 25B isoform 4 Cell division cycle 25B isoform 5 Dual specificity phosphatase Cdc25B EC 3.1.3.48 M phase inducer phosphatase 2 M-phase inducer phosphatase 2 MPIP2_HUMAN |
| Molecular Weight(MW) | 65 kDa |
| Cellular Localization | Cytoplasm, Cytoskeleton. |
| SwissProt ID | P30305 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
