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OM681987
Discount Price
OM681987-100ul
100ul
Product Profile
Product Name Anti-Phospho-CDC25A (Ser75)[Ser76] antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser75/Ser76
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CDC25A
Gene Synonyms CDC25A2
Gene Full Name cell division cycle 25A
Gene Summary CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alternative Names Cdc 25a
CDC25A
CDC25A2
CDC25A2 CAG isoform
Cell division cycle 25 homolog A (S. pombe)
Cell division cycle 25A
Cell division cycle 25A isoform a
Cell division cycle 25A isoform b
D9Ertd393e
Dual specificity phosphatase Cdc25A
M phase inducer phosphatase 1
M-phase inducer phosphatase 1
MGC115549
MPIP1_HUMAN
Molecular Weight(MW) 59 kDa
Cellular Localization Cytoplasm, Cytosol, Nucleoplasm, Nucleus.
Database Links
SwissProt ID P30304
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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