| Gene Symbol |
GRIN1
|
| Gene Synonyms |
NR1 MRD8 hNR1 GluN1 NMDA1 DEE101 NDHMSD NDHMSR NMD-R1 NMDAR1 |
| Gene Full Name |
glutamate ionotropic receptor NMDA type subunit 1 |
| Gene Summary |
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] |
| Alternative Names |
GluN1 Glutamate [NMDA] receptor subunit zeta-1 Glutamate receptor ionotropic N methyl D aspartate 1 Glutamate receptor ionotropic N-methyl-D aspartate subunit 1 glutamate receptor ionotropic NMDA 1 Grin1 MRD8 N methyl D aspartate receptor N methyl D aspartate receptor channel subunit zeta 1 N methyl D aspartate receptor subunit NR1 N-methyl-D-aspartate receptor subunit NR1 NMD-R1 NMDA 1 NMDA R1 NMDA receptor 1 NMDA1 NMDAR NMDZ1_HUMAN NR1 |
| Molecular Weight(MW) |
105 kDa |
| Cellular Localization |
Cell membrane, Postsynaptic cell membrane, Postsynaptic density membrane, Synaptic cell membrane. |