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Anti-Phospho-ZO-2 (Tyr1118) antibody

Catalog Number:OM682160
OM682160
Discount Price
OM682160-100ul
100ul
Product Profile
Product Name Anti-Phospho-ZO-2 (Tyr1118) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Tyr1118
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol TJP2
Gene Synonyms ZO2
X104
FHCA1
PFIC4
DFNA51
DUP9q21.11
C9DUPq21.11
Gene Full Name tight junction protein 2
Gene Summary This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Alternative Names C9DUPq21.11
DFNA51
DUP9q21.11
Friedreich ataxia region gene X104 (tight junction protein ZO-2)
MGC26306
PFIC4
Tight junction protein 2
Tight junction protein ZO 2
Tight junction protein ZO-2
TJP2
X104
ZO 2
ZO-2
ZO2
ZO2_HUMAN
Zona occludens 2
Zona occludens protein 2
Zonula occludens protein 2
Molecular Weight(MW) 134 kDa
Cellular Localization Cell junction, Cell membrane, Membrane, Nucleus, Tight junction.
Database Links
SwissProt ID Q9UDY2
Application

ELISA

Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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